منابع مشابه
SCIENTIFIC REPORT Identification of monosomy 3 in choroidal melanoma by chromosome in situ hybridisation
Background/aims: In uveal melanoma monosomy 3 is emerging as a significant indicator of a poor prognosis. To date most cytogenetic studies of uveal melanoma have utilised fresh tissue or DNA extracted from tissue sections. In this study chromosome in situ hybridisation (CISH) was used to study monosomy 3 in tissue sections. The copy number of chromosome 3 was determined and related to patient s...
متن کاملHeterogeneity of monosomy 3 in fine needle aspiration biopsy of choroidal melanoma
PURPOSE To report on the heterogeneity of monosomy 3 in a fine needle aspiration biopsy obtained transsclerally from choroidal melanoma for prognosis. METHODS All clinical records for patients who had been diagnosed with choroidal melanoma and underwent iodine-125 plaque brachytherapy with intraoperative transscleral fine needle aspiration biopsy from January 2005 to August 20, 2011, and who ...
متن کاملMonosomy 3 predicts death but not time until death in choroidal melanoma.
PURPOSE To study whether monosomy 3 can predict time until death caused by metastatic melanoma, whether life expectancy can be predicted in patients after surgical excision of a melanoma displaying monosomy 3, and to confirm the prognostic value of monosomy 3 and its correlation with tumor histology. METHODS Archival specimens from 71 patients who died of metastatic melanoma and 40 patients w...
متن کاملIdentification of monosomy 3 in choroidal melanoma by chromosome in situ hybridisation.
BACKGROUND/AIMS In uveal melanoma monosomy 3 is emerging as a significant indicator of a poor prognosis. To date most cytogenetic studies of uveal melanoma have utilised fresh tissue or DNA extracted from tissue sections. In this study chromosome in situ hybridisation (CISH) was used to study monosomy 3 in tissue sections. The copy number of chromosome 3 was determined and related to patient su...
متن کاملOrange pigment sediment overlying small choroidal melanoma.
Comment. To our knowledge, only 2 other studies have reported death secondary to cerebrovascular complications of APMPPE. In our case, like the 2 other reports, death occurred when oral prednisone was rapidly tapered to a dose of 20 mg/d. From a review of 9 patients with APMPPE who had strokes, patients were less likely to have a second stroke or die if they received high-dose corticosteroids (...
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ژورنال
عنوان ژورنال: Middle East African Journal of Ophthalmology
سال: 2010
ISSN: 0974-9233
DOI: 10.4103/0974-9233.65487